31 research outputs found

    Leading for What, Leading for Who? An International Comparative Analysis of University Presidents’ Leadership Amid COVID-19

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    The COVID-19 pandemic presented a unique shared challenge for all HEIs leaders around the world. Besides balancing institutional tasks and ensuring the health and safety of the campus community, university presidents were challenged with promoting equity and showing empathy in their leadership. Framed by Henry Mintzberg’s (1973) theory on managerial roles, this study uses in-depth interviews of 14 university presidents in eight countries, to understand how they enacted different roles in leading their institutions through a global crisis. Despite differences among presidential leadership styles in diverse contexts, findings from the study show that leadership roles shifted from securing their institution’s financial and academic stability to securing the well-being of the people within and outside their organization in the face of crisis

    Іншомовні аспекти фахової між культурної комунікації в сучасній вітчизняній і зарубіжній науковій літературі

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    У статті розглядаються основні напрямки сучасних вітчизняних і зарубіжних наукових досліджень з іншомовної фахової міжкультурної комунікації. Aspects of the professional foreign language of intercultural communication in modern domestic and foreign scientific literature. The paper discusses the main directions of current domestic and foreign scientific research in the field of professional foreign language intercultural communication

    Addressing Profiles of Systemic Inflammation Across the Different Clinical Phenotypes of Acutely Decompensated Cirrhosis

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    Background: Patients with acutely decompensated cirrhosis (AD) may or may not develop acute-on-chronic liver failure (ACLF). ACLF is characterized by high-grade systemic inflammation, organ failures (OF) and high short-term mortality. Although patients with AD cirrhosis exhibit distinct clinical phenotypes at baseline, they have low short-term mortality, unless ACLF develops during follow-up. Because little is known about the association of profile of systemic inflammation with clinical phenotypes of patients with AD cirrhosis, we aimed to investigate a battery of markers of systemic inflammation in these patients. Methods: Upon hospital admission baseline plasma levels of 15 markers (cytokines, chemokines, and oxidized albumin) were measured in 40 healthy controls, 39 compensated cirrhosis, 342 AD cirrhosis, and 161 ACLF. According to EASL-CLIF criteria, AD cirrhosis was divided into three distinct clinical phenotypes (AD-1: Creatinine<1.5, no HE, no OF; AD-2: creatinine 1.5–2, and or HE grade I/II, no OF; AD-3: Creatinine<1.5, no HE, non-renal OF). Results: Most markers were slightly abnormal in compensated cirrhosis, but markedly increased in AD. Patients with ACLF exhibited the largest number of abnormal markers, indicating “full-blown” systemic inflammation (all markers). AD-patients exhibited distinct systemic inflammation profiles across three different clinical phenotypes. In each phenotype, activation of systemic inflammation was only partial (30% of the markers). Mortality related to each clinical AD-phenotype was significantly lower than mortality associated with ACLF (p < 0.0001 by gray test). Among AD-patients baseline systemic inflammation (especially IL-8, IL-6, IL-1ra, HNA2 independently associated) was more intense in those who had poor 28-day outcomes (ACLF, death) than those who did not experience these outcomes. Conclusions: Although AD-patients exhibit distinct profiles of systemic inflammation depending on their clinical phenotypes, all these patients have only partial activation of systemic inflammation. However, those with the most extended baseline systemic inflammation had the highest the risk of ACLF development and death
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